French: Biologie des systèmes
German: Systembiologie, Systeomik
Italian: Biologia dei sistemi
Systems biology aims at a systems level understanding of control and regulation processes in a living organism. As a transdisciplinary research field it integrates methods from systems theory, biology, biochemistry, medicine, mathematics, physics, technology and computer science.
Systems biology views organisms as integrated and interacting networks of genes, proteins, control circuits, communication processes and biochemical reactions which give rise to life. Its subject is to understand and model metabolic processes of living systems in several organisational levels like cell, tissue, organ and body, in a qualitative and quantitative manner.
Emphasis of systems biology is focussed on interactions among components of the organism that are viewed as part of one system. Common methods are mathematical modelling and computer simulations ("in silico").
- Alon U. An Introduction to Systems Biology: Design Principles of Biological Circuits. Chapman and Hall/CRC, 2007. ISBN 1584886420
- Kitano, H. Foundations of Systems Biology. MIT Press, 2001. ISBN 0262112663
- Institute for Systems Biology, Seattle, WA, USA
- www.systems-biology.org - a portal site for systems biology
- Chair in Systems Biology and Bioinformatics, University of Rostock, Germany
- Förderschwerpunkt Systembiologie, Bundesministerium für Bildung und Forschung (in German)
- Systems biology for cyberneticians
- SBML.org - The home site for the Systems Biology Markup Language (SBML)